endoxifen

English

Noun

endoxifen (uncountable)

1. A metabolite of tamoxifen, 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol, that has similar properties
   • 2015 July 16, “Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients”, in PLOS ONE‎^[1], →DOI:

     It is described as a prodrug since most of its antiestrogen effects are exerted through its hydroxylated metabolites 4-OH-tamoxifen and endoxifen.