epimutation

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English[edit]

Etymology[edit]

From epi- +‎ mutation; compare epigenetic.

Noun[edit]

epimutation (plural epimutations)

  1. (genetics) A heritable change in gene expression that does not affect the actual base pair sequence of DNA.
    • 2005, Eva Jablonka and Marion J. Lamb, Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life,[1] MIT Press, ISBN 0-262-10107-6, page 248,
      The first sign of cellular abnormality in some tumors is an epimutation—a change in heritable chromatin marks, such as an increase or decrease in the density of DNA methylation.

See also[edit]