amidophosphoribosyltransferase

English

Structure of the ATase tetramer.

Etymology

From amido +‎ phosphoribosyltransferase

Pronunciation

• IPA^(key): /əˌmiːdoʊˌfɒsfəˌraɪbəʊzɪlˌtrænsfəˈreɪs/

Noun

amidophosphoribosyltransferase (uncountable, abbreviation ATase)

1. (biochemistry) An enzyme that catalyzes the first committed step in purine synthesis, converting PRPP and glutamine into a precursor used to make purine nucleotides such as adenine and guanine.