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- The action of breathing or blowing into or on.
- 1902, Henry James, The Wings of the Dove:
- From the oracle the sound did come—or at any rate the sense did, a sense all accordant with the insufflation she had just seen working.
- 2004, Daniel B. Silver, Refuge in Hell: How Berlin's Jewish Hospital Outlasted the Nazis, page 83
- He was the inventor of the procedure for flexible sigmoidoscopy using insufflation (inflating the sigmoid colon with air) that still is practiced today.
- The result of breathing or blowing into or on.
- The ritual breathing onto the water used for baptism