bandshift assay
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English
[edit]Noun
[edit]bandshift assay (plural bandshift assays)
- (biochemistry) A type of assay using gel electrophoresis, in which the mobility of a DNA or RNA probe alone is compared to its mobility in combination with a particular protein, so as to measure the degree and nature of binding between the protein and DNA or RNA.
- 2001 May 11, Peter Baumann, Thomas R. Cech, “Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans”, in Science[1], volume 292, number 5519, , pages 1171–1175:
- In bandshift assays, hPot1p bound to the G-rich strand of human telomeric DNA.
See also
[edit]- Electrophoretic mobility shift assay on Wikipedia.Wikipedia