cystine knot

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Noun

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cystine knot (plural cystine knots)

  1. (biochemistry) A protein structural motif containing three disulfide bridges formed from pairs of cysteine residues. The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, resulting in a rotaxane substructure. This motif stabilizes protein structure and is conserved in proteins across various species.