deorphanization

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English

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Etymology

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de- +‎ orphan +‎ -ization

Noun

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deorphanization (uncountable)

  1. The development of a drug so that it is no longer an orphan drug.
    • 2016 January 23, “The Subcellular Dynamics of the Gs-Linked Receptor GPR3 Contribute to the Local Activation of PKA in Cerebellar Granular Neurons”, in PLOS ONE[1], →DOI:
      The future deorphanization of GPR3 and clarifying its local dynamics may provide a clearer understanding of GPR3 neuronal expression and how it functionally activates the downstream signaling pathways.