macrolipasemia

English

Etymology

macrolipase +‎ -emia

Noun

macrolipasemia (usually uncountable, plural macrolipasemias)

1. The presence of macrolipases in the blood; when clinically detected, macrolipasemia has usually produced hyperlipasemia because renal clearance does not handle the macromolecules of enzyme in the same way that it would handle normal-sized enzyme molecules.
   • 2000, Goto H, Wakui H, Komatsuda A, Imai H, Miura AB, Fujita K, “Simultaneous macroamylasemia and macrolipasemia in a patient with systemic lupus erythematosus in remission”, in Internal Medicine, volume 39, number 12, →PMID, pages 1115–1118:

     We report the fourth case of simultaneous macroamylasemia and macrolipasemia. A 39-year-old woman had been treated for systemic lupus erythematosus from 1982 to 1993. She was found to have an unexplained increase in serum amylase and lipase activities since 1996. […] In the situation of atypical clinical features associated with hyperamylasemia and hyperlipasemia, the possibility of macroenzymes should be considered.