maytansanoid
Jump to navigation
Jump to search
English
[edit]Noun
[edit]maytansanoid
- Misspelling of maytansinoid.
- 2015 July 15, “Caveolin-1 Dependent Endocytosis Enhances the Chemosensitivity of HER-2 Positive Breast Cancer Cells to Trastuzumab Emtansine (T-DM1)”, in PLOS ONE[1], :
- HER-2-based ADC targeting have been investigated for clinical application in breast cancer treatment [11, 12 ] using trastuzumab emtasime (trastuzumab-DM1; T-DM1), in which trastuzumab is conjugated through a stable thioether bond to the maytansanoid derivative emtasine.