knockin

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English[edit]

Alternative forms[edit]

Noun[edit]

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knockin (plural knockins)

  1. (genetics) The insertion of a cDNA sequence at a particular locus in an organism's chromosome
    • 2015 July 8, “Non-Invasive Quantification of Cartilage Using a Novel In Vivo Bioluminescent Reporter Mouse”, in PLOS ONE[1], →DOI:
      The advantage of this design is that the targeted knockin retains the intact endogenous aggrecan locus and expresses the tamoxifen-inducible CreERT2 protein from a second IRES-driven open reading frame.