From Spanish, from Santiago, a combination of "Sant’ Iago", and "Saint James". Sant is from Latin Sanctus, "holy" or "saint". Iago is a northwestern Spanish form from Latin Jacobus, "James". The name Diego is sometimes confused with the Latin name Didacus.
- The name Saint Diego (Sant’ Iago, Saint James of Alcalá), sometimes also confused or connected with the Latin name Didacus.
- Places named after Saint Diego.