globomycin

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English

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Noun

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globomycin

  1. A cyclic peptide antibiotic which inhibits the growth of enteric Gram-negative bacteria through cell wall synthesis inhibition
    • 2015 July 4, Paula Roszczenko et al., “Helicobacter pylori HP0377, a member of the Dsb family, is an untypical multifunctional CcmG that cooperates with dimeric thioldisulfide oxidase HP0231”, in BMC Microbiology[1], volume 15, →DOI:
      It has been shown that the two main strategies commonly used to confirm lipid modification of a protein (radiolabeling with palmitic acid and inhibition of the signal peptidase II activity by globomycin) have not worked in H. pylori [ 49, 50 ].