auristatin
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English
[edit]Noun
[edit]auristatin (plural auristatins)
- Any of a family of particular antineoplastic agents
- 2015 July 11, “Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy”, in PLOS ONE[1], :
- Here, we examine the stability of a non-cleavable Amino-PEG6-based linker bearing the monomethyl auristatin D (MMAD) payload site-specifically conjugated at multiple positions on an antibody.