cephalosporinase

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English[edit]

Etymology[edit]

cephalosporin +‎ -ase

Noun[edit]

cephalosporinase (plural cephalosporinases)

  1. (biochemistry) Any enzyme that hydrolyses (the lactam ring of a ) cephalosporin
    • 2015 September 24, “In Vivo Evolution of Bacterial Resistance in Two Cases of Enterobacter aerogenes Infections during Treatment with Imipenem”, in PLOS ONE[1], DOI:10.1371/journal.pone.0138828:
      Resistance to β-lactams is mainly due to enzymatic degradation by a chromosomal cephalosporinase, plasmid-mediated broad spectrum β-lactamases, and recently acquired carbapenemases [4, 6, 7, 9 –14 ].