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The structural form of a clobenpropit molecule.


clobenpropit (uncountable)

  1. (biochemistry) A histamine H3 antagonist that has neuroprotective effects via stimulation of GABA release in the brain. Chemical symbol: C14H17ClN4S.


  • Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007), “The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes”, in Eur. J. Pharmacol., volume 567, issue 3, →DOI, →PMID, pages 206–10
  • Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z. (2007), “The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.”, in European Journal of Pharmacology, volume 563(1-3), →PMID, pages 117-23