cyclopropylated
Jump to navigation
Jump to search
English[edit]
Adjective[edit]
cyclopropylated (not comparable)
- (organic chemistry) Modified by the addition of cyclopropyl group(s)
- 2013 September 15, Anita Y. M. Howe, Srikanth Venkatraman, “The Discovery and Development of Boceprevir: A Novel, First-generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease”, in Journal of Clinical and Translational Hepatology[1], volume 1, :
- Cyclization of the N-methyl group to a P2 cyclopropyl group generated the cyclopropylated Analog 8, which had greater enzyme-binding affinity ( Ki * = 11 nmol/L) than Analog 6.