Definition from Wiktionary, the free dictionary
- Causing a loss of energy or strength.
1931, H.P. Lovecraft, The Whisperer in Darkness:
- Akeley, Noyes hastened to inform me, was glad and ready to see me; although his sudden attack of asthma would prevent him from being a very competent host for a day or two. These spells hit him hard when they came, and were always accompanied by a debilitating fever and general weakness.
- Nouns often used with "debilitating": illness, effect.