endotoxicity

English

Etymology

endo- +‎ toxicity

Noun

endotoxicity (countable and uncountable, plural endotoxicities)

1. The quality or degree of being endotoxic.
   • 2015 August 7, “Production of a Shigella sonnei Vaccine Based on Generalized Modules for Membrane Antigens (GMMA), 1790GAHB”, in PLOS ONE‎^[1], →DOI:

     Using a Shigella sonnei strain that was genetically modified to produce penta-acylated lipopolysaccharide (LPS) with reduced endotoxicity and to maintain the virulence plasmid encoding for the immunodominant O antigen component of the LPS, scale up of the process to GMP pilot scale was straightforward and gave high yields of GMMA with required purity and consistent results.