glyoxalase

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English[edit]

Etymology[edit]

glyoxal +‎ -ase

Noun[edit]

glyoxalase (countable and uncountable, plural glyoxalases)

  1. (biochemistry) Either of a pair of related thiol-dependent enzymes: glyoxalase І, which catalyses the isomerisation of the spontaneously formed hemithioacetal adduct between GSH and 2-oxoaldehydes (such as methylglyoxal) into S-2-hydroxyacylglutathione; and glyoxalase ІІ, which hydrolyses these thiolesters.