homodimerisation

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English

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Noun

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homodimerisation (plural homodimerisations)

  1. Alternative form of homodimerization
    • 2015 December 24, “Revealing Different Roles of the mTOR-Targets S6K1 and S6K2 in Breast Cancer by Expression Profiling and Structural Analysis”, in PLOS ONE‎[1], →DOI:
      IGF1 and IGF2 bind and activate the receptor tyrosine kinase IGF1R, leading to homodimerisation as well as heterodimerisation with the insulin receptor (INSR), subsequent IRS1 recruiting and downstream PI3K/AKT/mTOR activation.
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