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macro- +‎ thrombocytopenia


macrothrombocytopenia (countable and uncountable, plural macrothrombocytopenias)

  1. A form of thrombocytopenia characterised by unusually large platelets
    • 2015 July 16, “Artificial MiRNA Knockdown of Platelet Glycoprotein lbα: A Tool for Platelet Gene Silencing”, in PLOS ONE[1], DOI:10.1371/journal.pone.0132899:
      Absence or dysfunction of GPIb-V-IX results in the Bernard-Soulier Syndrome, a bleeding disorder characterised not only by impaired platelet adhesion, but also by macrothrombocytopenia, due to a disturbed link between the GPIb-V-IX complex and the underlying cytoskeleton during platelet and/or MK formation [17 ].