methoctramine

English

Structure of methoctramine

Etymology

Probably from meth(ylene) +‎ oc(tane) +‎ (te)tr(a)amine.

Pronunciation

• (General American) IPA^(key): /mɛθˈɑk.tɹəˌmiːn/

Noun

methoctramine (uncountable)

1. A polymethylene tetraamine that acts as a muscarinic antagonist
   • 2015 August 26, “Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1 G93A Lumbar Motoneurons”, in PLOS ONE‎^[1], →DOI:

     It has been recently demonstrated that hyperexcitation can be neuroprotective for SOD1 Mns and that the muscarinic receptor antagonist, methoctramine enhanced the accumulation of misfolded SOD1 proteins in these neurons.