pyrrolopyridine

English

Noun

pyrrolopyridine (countable and uncountable, plural pyrrolopyridines)

1. (organic chemistry) Any heterobicyclic compound containing fused pyrrole and pyridine rings
   • 2015 November 14, “Interaction of the N -(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode”, in PLOS ONE‎^[1], →DOI:

     A preliminary validation of the computational protocol was performed by reproducing the experimentally determined binding mode of the pyrrolopyridine inhibitor found in the crystal structure 3QK5, which showed the reliability of the procedure not only to reproduce the ligand binding, but also the position of key water molecules within the active site.