shotgun proteomics

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English

Noun

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shotgun proteomics (uncountable)

  1. (genetics) A laboratory method for the determining the identities of proteins in a mixture.
    • "Analogous to (shotgun sequencing), in shotgun proteomics, complex protein mixtures are digested into peptides, analyzed by tandem mass spectrometry, and computer algoriths then map the peptides onto proteins to dtermine the original content of the mixture." — Swanson & Washburn, pg. 719.

References

  • Swanson, Selene K; Washburn, Michael P. (2005) "The continuing evolution of shotgun proteomics". Drug Discovery Today. 10, 10/24, ppg. 719–725.
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