synaptotoxicity

English

Etymology

synapto- +‎ toxicity

Noun

synaptotoxicity (uncountable)

1. The quality of being synaptotoxic.
   • 2015 November 6, “The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy”, in PLOS ONE‎^[1], →DOI:

     Compared with vehicle-treated controls, rapamycin protected against the tau-induced neuronal loss, synaptotoxicity, reactive microgliosis and astrogliosis, and activation of innate neuroimmunity.