Definition from Wiktionary, the free dictionary
- (genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.
- 2002, Maloy, Stanley; French-Mischo, Stephanie (16 July 2002), "Synthetic Lethal Mutations" (in en), Microbial Genetics. San Diego State University. URL accessed on 10 December, 2009.
- 2008 12 September, Le Meur, Nolwenn; Gentleman, Robert, “Modeling synthetic lethality”, Genome Biology, volume 9, DOI:10.1186/gb-2008-9-9-r135, page R135: