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Named after John L.H. Langdon-Down (1828–1896), an English physician who described it in the late 1800s. The term was first used in 1961.
- (chiefly Britain, Canada) Condition caused by a chromosomal deficiency, whereby the patients bear a certain resemblance to the Mongoloid race, such as a small head and tilted eyelids.
More often known as Down syndrome in the US, and rarely so in the UK.
condition caused by chromosomal deficiency — see Down syndrome