Down syndrome

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A father and his son with Down syndrome

Alternative forms[edit]


Named after John Langdon Haydon Down (1828–1896), an English physician who first described the condition as a distinct form of mental disability in the 1860s.


Proper noun[edit]

Down syndrome

  1. (neurology, chiefly US) A medical condition caused by a chromosomal excess, whereby the patients bear a certain resemblance to the Mongoloid race, such as a small head and tilted eyelids, and typically have a delay in cognitive ability and physical growth. [from 1961.]

Usage notes[edit]

The condition is known only as Down's syndrome in the UK.



Further reading[edit]