brepocitinib

English

Noun

brepocitinib (uncountable)

1. (pharmacology) An experimental medication belonging to the class of Janus kinase inhibitors.
   • 2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2172:

     PF-06826647 is a TYK2-selective jakinib (68) currently in trials for the treatment of psoriasis, UC, and hidradenitis suppurativa; brepocitinib is a TYK2/JAK1 inhibitor that was assessed in a phase II trial of psoriasis where clinical responses were seen with all doses (69).