glucosepane

English

Noun

glucosepane (uncountable)

1. A lysine-arginine protein cross-linking product and advanced glycation end product derived from D-glucose.
   • 2015 September 5, Vincent M Monnier et al., “Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes”, in Cardiovascular Diabetology‎^[1], volume 14, →DOI:

     A direct role for methylglyoxal lysine dimer (MOLD) or MODIC crosslinks has been alluded to, though these are present in amounts 100 times lower than glucosepane in skin from diabetic individuals.