intercodon

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English[edit]

Etymology[edit]

inter- +‎ codon

Adjective[edit]

intercodon (not comparable)

  1. (genetics) Between codons

Noun[edit]

intercodon (plural intercodons)

  1. (genetics) The sequence of nucleic acid between specific codons
    • 2015 October 9, “HIV-1 and Human PEG10 Frameshift Elements Are Functionally Distinct and Distinguished by Novel Small Molecule Modulators”, in PLOS ONE[1], DOI:10.1371/journal.pone.0139036:
      Both have (i) slippery sequences (SS) of the form X XXY YYZ (U UUU UUA for HIV-1 and G GGA AAC for PEG10), (ii) different intercodons [26 ] (GGG and UCC respectively), (iii) distinct secondary structures (SStr) (extended stem-loop for HIV-1 and pseudoknot for PEG10), and (iv) the SStr start is within the intercodon in HIV-1, whereas it is two nucleotides downstream of the intercodon in PEG10. [] The different slippery sequences, intercodons, and downstream secondary structures facilitated a frameshift efficiency that was ~2.5-fold higher for PEG10 than for HIV-1 (Fig 1 ).