From mis- + affect.
misaffect (third-person singular simple present misaffects, present participle misaffecting, simple past and past participle misaffected)
- (obsolete) To dislike. [16th-17th c.]
- (obsolete) To affect in a negative way. [17th c.]
- 1621, Democritus Junior [pseudonym; Robert Burton], The Anatomy of Melancholy, Oxford: Printed by Iohn Lichfield and Iames Short, for Henry Cripps, OCLC 216894069:, Bk.I, New York, 2001, p.171:
- forasmuch as this malady is caused by precedent imagination, […] the brain must needs be primarily misaffected, as the seat of reason […]