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From mis- +‎ affect.


misaffect (third-person singular simple present misaffects, present participle misaffecting, simple past and past participle misaffected)

  1. (obsolete) To dislike. [16th-17th c.]
  2. (obsolete) To affect in a negative way. [17th c.]
    • 1621, Democritus Junior [pseudonym; Robert Burton], The Anatomy of Melancholy, Oxford: Printed by Iohn Lichfield and Iames Short, for Henry Cripps, OCLC 216894069; The Anatomy of Melancholy, 2nd corrected and augmented edition, Oxford: Printed by John Lichfield and James Short, for Henry Cripps, 1624, OCLC 54573970, (please specify |partition=1, 2, or 3):
      , Bk.I, New York, 2001, p.171:
      forasmuch as this malady is caused by precedent imagination, [] the brain must needs be primarily misaffected, as the seat of reason []