obatoclax

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English[edit]

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Noun[edit]

obatoclax (uncountable)

  1. An experimental drug candidate for the treatment of various cancers.
    • 2015 May 22, Georg Lenz, Martin Dreyling, “Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications”, in Cancers[1], volume 7, DOI:10.3390/cancers7020812:
      Chemotherapy resistance in ABC DLBCL might potentially be overcome by pharmacologic inhibition of MCL1, as treatment with the BH3-mimetic obatoclax induced apoptosis in MCL1-positive ABC DLBCL models.