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- A portion of DNA or RNA containing several consecutive pyrimidine bases
- 2015 July 25, “Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes”, in PLOS ONE, DOI:10.1371/journal.pone.0133482:
- However, mTOR-sensitive translatomes commonly include mRNAs with a 5’ terminal oligopyrimidine tract (TOP), such as those encoding ribosomal proteins, but not ISGs. Because these translatomes were obtained under conditions when ISG expression is not induced, we examined the mTOR-sensitive translatome in human WISH cells stimulated with IFN β.