perturbagen

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English

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Etymology

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From perturb +‎ -gen.

Noun

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perturbagen (plural perturbagens)

  1. A substance (typically a peptide) designed to disrupt intracellular processes, providing information about the operation of pathways and networks within a cell.
    • 2015 July 9, Maja Temerinac-Ott, Armaghan W Naik, Robert F Murphy, “Deciding when to stop: efficient experimentation to learn to predict drug-target interactions”, in BMC Bioinformatics[1], volume 16, →DOI:
      To address this problem, we have previously proposed a parametrization of perturbagen-target systems in which we characterize each system by its responsiveness (the probability that a perturbagen has an effect on a target) and its uniqueness (the probability that a perturbagen or target is different from others) [ 18 ].