proteoform

Definition from Wiktionary, the free dictionary
Jump to navigation Jump to search

English[edit]

Noun[edit]

proteoform (plural proteoforms)

  1. A specific molecular form of a protein product arising from a specific gene.
  2. Any of a group of related protein molecules arising from all combinatorial sources of variation giving rise to products arising from a single gene. These include products differing due to genetic variation, alternatively spliced RNA, transcripts, and post-translational modifications.

Pronunciation[edit]

  • (US) IPA(key): /ˈpɹoʊtiːoʊˌfɔɹm/

Usage notes[edit]

The term includes all PTMs classified by the PSI-MOD ontology (which uses PSI-MS standardized names for protein modifications), except those classified as reagent derivatized residues (MOD:00848) or isotope labeled residues (MOD:00702).

References[edit]