pseudopseudohypoparathyroidism

English

Etymology

Etymology tree

Pre-Greekder.?

Ancient Greek ψεύδω (pseúdō)

Proto-Indo-European *-os

Proto-Indo-European *-ēs

Proto-Hellenic *-ēs

Ancient Greek -ης (-ēs)

Ancient Greek -ής (-ḗs)

Ancient Greek ψευδής (pseudḗs)der.

Middle English pseudo-

English pseudo-

▲

English pseudo-

Proto-Indo-European *upó

Ancient Greek ῠ̔πό (hŭpó)

Ancient Greek ὑπο- (hupo-)der.

English hypo-

Proto-Indo-European *per-

Proto-Indo-European *preh₂-

Proto-Hellenic *pərai

Ancient Greek πᾰρᾰ́ (părắ)

Ancient Greek πᾰρᾰ- (pără-)der.

English para-

Proto-Indo-European *dʰwer-der.

Proto-Hellenic *tʰurā

Ancient Greek θῠ́ρᾱ (thŭ́rā)

Ancient Greek -εος (-eos)

Ancient Greek θῠρεός (thŭreós)

Proto-Indo-European *weyd-

Proto-Indo-European *-os

Proto-Indo-European *wéydos

Proto-Hellenic *wéidos

Ancient Greek εἶδος (eîdos)

▲

Ancient Greek -ης (-ēs)

Ancient Greek -ειδής (-eidḗs)

Ancient Greek θῠρεοειδής (thŭreoeidḗs)bor.

New Latin thyreoīdēsbor.

English thyroid

English parathyroid

Proto-Indo-European *-id-

Proto-Indo-European *-yéti

Proto-Indo-European *-idyéti

Proto-Hellenic *-íd͏̌d͏̌ō

Ancient Greek -ῐ́ζω (-ĭ́zō)

Proto-Indo-European *-mos

Proto-Indo-European *-mós

Ancient Greek -μός (-mós)

Ancient Greek -ισμός (-ismós)der.

English -ism

English hypoparathyroidism

English pseudohypoparathyroidism

English pseudopseudohypoparathyroidism

From pseudo- (“false”) + pseudohypoparathyroidism.

Pronunciation

• (Received Pronunciation) IPA^(key): /ˌsjuː.dəʊˌsjuː.dəʊˌhaɪ.pəʊ.pæɹ.əˈθaɪ.ɹɔɪd.ɪzəm/
• (US) IPA^(key): /ˌsuː.doʊˌsuː.doʊˌhaɪ.poʊ.pæɹ.əˈθaɪ.ɹɔɪd.ɪzəm/

• Audio (UK):

  (file)

• Audio (US):

  (file)

• Hyphenation: pseu‧do‧pseu‧do‧hy‧po‧par‧a‧thy‧roid‧ism

Noun

pseudopseudohypoparathyroidism (plural pseudopseudohypoparathyroidisms, abbreviation PPHP)

1. (genetics) A genetic condition characterized by physical features similar to pseudohypoparathyroidism such as short stature, round facies, and subcutaneous ossifications, but without biochemical abnormalities like calcium or phosphate imbalance, due to normal end-organ responsiveness to parathyroid hormone.

   Coordinate terms: euparathyroidism, hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism

   • 2007, Dominique N. Long, Sarah McGuire, Michael A. Levine, Lee S. Weinstein, Emily L. Germain-Lee, Body Mass Index Differences in Pseudohypoparathyroidism Type 1a Versus Pseudopseudohypoparathyroidism May Implicate Paternal Imprinting of Gαs in the Development of Human Obesity: Journal of Clinical Endocrinology & Metabolism, volume 92, number 3, pages 1073–1079:

     Because Gαs is paternally imprinted in certain hormone target tissues, maternal inheritance of AHO leads to multihormone resistance [pseudohypoparathyroidism type 1a (PHP1a)], whereas paternal inheritance leads to AHO alone [pseudopseudohypoparathyroidism (pseudoPHP)]. Classically, the obesity in AHO is described as occurring similarly in both conditions.

Synonyms

• pseudoPHP

Coordinate terms

• Albright hereditary osteodystrophy