stuff up

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stuff up ‎(third-person singular simple present stuffs up, present participle stuffing up, simple past and past participle stuffed up)

  1. (idiomatic) To ruin
    Don't drink tonight, because it'll stuff you up
  2. (Britain, Australia) To make a big mistake
    The reason we lost the match is due to the goalkeeper stuffing up
  3. cause to be blocked
    My nose is all stuffed up so I'm speaking funny