sympathicolytic

English

Adjective

sympathicolytic (comparative more sympathicolytic, superlative most sympathicolytic)

1. Alternative form of sympatholytic.
   • 1952, A Textbook of Pharmacology: Principles and Application of Pharmacology to the Practice of Medicine, pages 812, 824:

     The sympathicolytic and adrenolytic actions are masked in this case and are overshadowed by the pronounced central action of these alkaloids on the vasomotor center. […] Dihydroergocornine (DHO 180). Crude extracts of ergot are both oxytocic and sympathicolytic.

   • 1954, Etherington, Joan, assistant, Wolstenholme, Gordon Ethelbert Ward, Cameron, Margaret P., editors, Hypertension: Humoral and Neurogenic Factors, London: J. & A. Churchill, Ltd., page 73:

     This, we think, rather confirms Dr. Page’s findings that Apresoline inhibits somewhat specifically the effect of stimulation of the central end of the vagus, although some peripheral sympathicolytic effect is present too. / In contrast to the effect of these three drugs, the Rauwolfia alkaloid, Serpasil, has no sympathicolytic and no ganglionic blocking activity.

   • 2006, Kamen G. Usunoff, Anastas Popratiloff, Oliver Schmitt, Andreas Wree, Functional Neuroanatomy of Pain, Springer, pages 51–52:

     Sympathectomy has been shown to alleviate allodynia in animal models, some patients with causalgia respond positively to sympathicolytic procedures, and injection of epinephrine in a stump neuroma may induce intense pain (Chabal et al. 1992; Choi and Rowbotham 1997; Attal and Bouhassira 1999).

Noun

sympathicolytic (plural sympathicolytics)

1. Alternative form of sympatholytic.
   • 1954, Etherington, Joan, assistant, Wolstenholme, Gordon Ethelbert Ward, Cameron, Margaret P., editors, Hypertension: Humoral and Neurogenic Factors, London: J. & A. Churchill, Ltd., page 73:

     Bein: We have compared in the cat the influence of various drugs with a different point of attack (namely a sympathicolytic, “Regitine”; a ganglionic blocking substance, “pendiomide”; a phthalazine derivative, “Apresoline”; and a recently isolated alkaloid from Rauwolfia serpentina, “Reserpine” or “Serpasil”) on the blood pressure rise, produced either by stimulation of the central end of the vagus, or, for comparison, by adrenaline or by noradrenaline.

   • 1968, Handbook of Experimental Pharmacology, Springer-Verlag, →ISBN, page 164:

     The rat is pretreated with a sympathicolytic for the following reasons: / In an untreated rat intravenous injection of 0.1–0.5 ml 0.9% NaCl solution (the permitted volume of injection) elicits a pressor reaction. This reaction is completely prevented by means of a sympathicolytic (Dekanski, 1952).

   • 1969, Review of Czechoslovak Medicine, volume 15, page 70:

     Fig. 7. Action of sympathicolytics on platelet aggregation induced by adrenaline in a concentration of 5.10⁻⁵M

   • 1970, Proceedings: Biological and medical sciences, volume 73, pages 9, 13:

     In total, the ECG remained therefore unchanged after treatment with sympathicolytics in 15 men. […] A possibly present depression of the ST-segment and inversion of the T-wave due to myocarditis does not change after application of the sympathicolytics, which is also true for the experimentally provoked ST-depression caused by damage to the myocardium (Furberg, 1967, 1968).

   • 1993, Delaware Medical Journal, volume 65, page 289:

     Yocon* is indicated as a sympathicolytic and mydriatric.

   • 2005, Sophie Mataniele Mogotlane, Joyce Mokoena, Motshedisi Eunice Chauke, Anne Young, editors, Juta’s Manual of Nursing: Medical Surgical Nursing, Juta Academic, →ISBN, page 12-29:

     Centrally acting sympathicolytics cause a decrease in the sympathetic outflow from the brainstem. This reduction in sympathetic outflow brings about vasodilatation of the peripheral vascular bed with a concomitant drop in the blood pressure