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- (pharmacology) A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
- 2007 February 8, Jeremy Pearce, “Leon J. Thal, Neurologist Who Led Study for Alzheimer’s Drugs, Dies at 62”, in New York Times:
- In the 1980s, Dr. Thal, a neurologist, helped lead successful clinical trials of tacrine, a cholinesterase inhibitor drug that was approved by the Food and Drug Administration in 1993.
- “tacrine”, in Lexico, Dictionary.com; Oxford University Press, 2019–present.
- “tacrine”, in Merriam–Webster Online Dictionary.