anoikis

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English[edit]

Etymology[edit]

Pseudo-Greek coinage intended to have the sense "homelessness". Compare Ancient Greek ἄνοικος ‎(ánoikos, homeless wanderer).

Pronunciation[edit]

Noun[edit]

anoikis ‎(uncountable)

  1. (cytology) The form of apoptosis, or programmed cell death, that occurs when a cell becomes dislodged from its matrix
    • 2009 August 19, Zachary T. Schafer et al., “Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment”, in Nature, volume 461, number 7260, DOI:10.1038/nature08268, pages 109-113:
      Loss of matrix attachment of cultured epithelial cells activates a caspase-mediated apoptotic program known as anoikis.

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