epimutation

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See also: épimutation

English[edit]

Etymology[edit]

From epi- +‎ mutation; compare epigenetic.

Pronunciation[edit]

Noun[edit]

epimutation (plural epimutations)

  1. (genetics) A heritable change in gene expression that does not affect the actual base pair sequence of DNA.
    • 2005, Eva Jablonka, Marion J. Lamb, Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life[1], MIT Press, →ISBN, page 248:
      The first sign of cellular abnormality in some tumors is an epimutation—a change in heritable chromatin marks, such as an increase or decrease in the density of DNA methylation.

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