idiotypy

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English[edit]

Etymology[edit]

ideotype +‎ -y

Noun[edit]

idiotypy (uncountable)

  1. (immunology) The immune recognition of one ideotype by a system sensitized to other ideotypes in the same group.
    • 2012, Frank Putnam, The Plasma Proteins V3: Structure, Function, and Genetic Control, →ISBN:
      Idiotypy was first recognized serologically by use of antisera prepared in animals of the same species
    • 2014, Argyrios N Theofilopoulos, Constantin A. Bona, The Molecular Pathology of Autoimmune Diseases, →ISBN, page 364:
      The ontogeny of natural ids and anti-ids is another area in need of more detailed study, but it seems that idiotypy may appear during the formative stages of repertoire selection, even before contact with foreign antigens.
    • 2014, Alfred Nisonoff, John E. Hopper, Susan B. Spring, The Antibody Molecule, →ISBN, page 444:
      The restriction of idiotypic determinants to antibodies of a single specificity from an individual donor clearly differentiates idiotypy from allotypy, since allotypic determinants are shared by various antibodies of an individual.
  2. The study or use of ideotypes within medicine.
    • 1984, Heinz Köhler, Jacques Urbain, Pierre-André Cazenave, Idiotypy in Biology and Medicine, →ISBN, page xix:
      Today a new dimension in idiotypy is developing, which has the potential of broad applications in biology medicine.