Jump to navigation Jump to search
ketoreduction (plural ketoreductions)
- (organic chemistry) The reduction of a ketone (typically to an alcohol)
- 2015 July 11, “Functional Characterization of a Ketoreductase-Encoding Gene med -ORF12 Involved in the Formation of a Stereospecific Pyran Ring during the Biosynthesis of an Antitumor Antibiotic Medermycin”, in PLOS ONE, DOI:10.1371/journal.pone.0132431:
- In addition to that, a co-expression system composed of 6 act earlier genes (KS-, CLP-, ACP-, KR-, ARO- and CYC-encoding genes) together with med-ORF12 could result in the production of (S)-DNPA 7, proposing that Med-ORF12 could catalyze a stereospecific ketoreduction at C3 of the bicyclic intermediate 4, formed by 6 act earlier genes [12, 19 ].