protease

See also: protéase

English

Etymology

Etymology tree

English prote(in)

Proto-Indo-European *dwóh₁

▲

Proto-Indo-European *trísinflu.

Proto-Indo-European *dwísder.

Ancient Greek διά (diá)

Ancient Greek δῐᾰ- (dĭă-)

Proto-Indo-European *steh₂-redup.

Proto-Indo-European *-ti

Proto-Indo-European *stísteh₂ti

Proto-Hellenic *hístāmi

Ancient Greek ῐ̔́στημῐ (hĭ́stēmĭ)

Ancient Greek δῐῐ̈́στημῐ (dĭĭ̈́stēmĭ)

Ancient Greek δῐᾰ́στᾰσῐς (dĭắstăsĭs)

English diastase

English -ase

English protease

From prote(in) + -ase.

Pronunciation

• IPA^(key): /ˈpɹəʊtɪeɪz/

• Audio (Southern England):

  (file)

Noun

protease (plural proteases)

1. (biochemistry) An enzyme that cuts or cleaves proteins.
   • 1903 November 2, S. G. Hedin, “On the presence of a proteolytic enzyme in the normal serum of the ox”, in The Journal of Physiology, volume 30, number 2, page 195:

     As a matter of fact the casein protease digests boiled and coagulated serum far more easily than unboiled serum, as set forth by the following experiments.

   • 1948 September 20, Margaret R. McDonald, “A method for the preparation of "protease-free" crystalline ribonuclease”, in Journal of General Physiology, volume 32, number 1, page 39:

     All were tested for their ability to clot milk and to hydrolyze denatured hemoglobin, egg albumin, protamine (salmon), histone (calf thymus), and benzoyl-l-arginineamide. In no case was any trace of protease activity detected.

   • 2015, Raja Sivamani, Jared R. Jagdeo, Peter Elsner, Cosmeceuticals and Active Cosmetics:

     For our purposes, it is sufficient to note that dysregulation of desquamatory protease activity in the SC is often involved in conditions of compromised skin barrier.

Derived terms

• antiprotease
• autoprotease
• Bowman-Birk protease inhibitor
• coprotease
• endoprotease
• exoprotease
• glycoprotease
• leucoprotease
• leukoprotease
• mercapto protease
• metalloprotease
• neuroprotease
• phosphoprotease
• preprotease
• proprotease
• protease inhibitor
• proteasic
• proteasome
• pseudoprotease
• rhomboid protease
• saquinavir
• secretory leukocyte protease inhibitor
• sialoglycoprotease

Translations

enzyme

• Catalan: proteasa f
• Chinese:

  Mandarin: 蛋白酶 (zh) (dànbáiméi)

• Czech: proteáza f
• Finnish: proteaasi
• French: protéase (fr)
• German: Protease f, Peptidase f, Proteinase f
• Hindi: प्रोभूजिनेद m (probhūjined)
• Irish: próitéáis
• Italian: proteasi (it)
• Japanese: プロテアーゼ (puroteāze), 蛋白質分解酵素 (たんぱくしつぶんかいこうそ, tanpakushitsu bunkai kōso)
• Kazakh: ақуызды ыдырататын фермент (aquwızdı ıdıratatın ferment)
• Korean: 프로테아제 (peuroteaje), 단백질 분해 효소 (danbaekjil bunhae hyoso)
• Polish: peptydaza f
• Portuguese: protease (pt) f
• Spanish: proteasa f
• Welsh: proteas m

References

• protease on Wikipedia.Wikipedia

Anagrams

• Asterope, operates, soap tree, soaptree

Portuguese

Alternative forms

• protéase

Etymology

From proteína (“protein”) + -ase.

Pronunciation

• (Brazil) IPA^(key): /pɾo.teˈa.zi/

• (Portugal) IPA^(key): /pɾɔˈtja.zɨ/

Noun

protease f (plural proteases)

1. (biochemistry) protease (any of a group of enzymes that cleave proteins)

Further reading

• “protease”, in Dicionário Aulete Digital (in Portuguese), Rio de Janeiro: Lexikon Editora Digital, 2008–2026
• “protease”, in Dicionário Priberam da Língua Portuguesa (in Portuguese), Lisbon: Priberam, 2008–2026