sclerosis

English

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sclerosis

From Ancient Greek σκλήρωσις (sklḗrōsis, “hardening”), from σκληρόω (sklēróō, “to harden”), from σκληρός (sklērós, “hard”); by surface analysis, sclero- +‎ -osis.

(Received Pronunciation) IPA^(key): /skləˈɹəʊ.sɪs/
(General American, Canada) IPA^(key): /skləˈɹoʊ.sɪs/
- Audio (Milwaukee, Wisconsin): (file)
(General Australian) IPA^(key): /skləˈɹəʉ.sɪs/
(New Zealand) IPA^(key): /skləˈɹɐʉ.səs/
Hyphenation: scle‧ro‧sis
Rhymes: -əʊsɪs

sclerosis (countable and uncountable, plural scleroses)

(pathology) The abnormal hardening of body tissues, such as an artery; the appearance of hardenings, indurations, lesions, nodules.
Synonyms: hardening, fibrosis (in some contexts), induration
- 2025 April 10, Dan Heching, “Eric Dane shares that he has been diagnosed with ALS”, in CNN‎^[1]:
  The “Euphoria” and “Grey’s Anatomy” actor announced on Thursday that he has been diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease.
Inability to create change or excessive resistance to change.
- 2019 December 6, Charles Hugh Smith, Suppressing Dissent Guarantees Disorder and Collapse‎^[2]:
  Suppressing dissent dooms the society to sclerosis, decline and collapse.

abnormal hardening of body tissues

Etymology tree

Ancient Greek σκλήρωσις (sklḗrōsis)bor.

Latin sclērōsis

Borrowed from Ancient Greek σκλήρωσις (sklḗrōsis, “hardening”).

sclērōsis f (genitive sclērōsis or sclērōseōs or sclērōsios); third declension

Third-declension noun (Greek-type, i-stem).

	singular	plural
nominative	sclērōsis	sclērōsēs sclērōseis
genitive	sclērōsis sclērōseōs sclērōsios	sclērōsium
dative	sclērōsī	sclērōsibus
accusative	sclērōsim sclērōsin sclērōsem¹	sclērōsēs sclērōsīs
ablative	sclērōsī sclērōse¹	sclērōsibus
vocative	sclērōsis sclērōsi	sclērōsēs sclērōseis

¹Found sometimes in Medieval and New Latin.