of course

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From literal meaning "of the ordinary course of events". Oldest attestation as "of course" from the 1540s, but previously used in the same sense as "by course" (then-spelled "bi cours", sic) since ca. 1300. (Source: Etymonline.com)


of course (not comparable)

  1. (idiomatic) Indicates enthusiastic agreement.
    Of course I'll go with you.
  2. (idiomatic) Acknowledges the validity of the associated phrase.
    Of course, there will be a few problems along the way.
  3. (idiomatic) Asserts that the associated phrase should not be argued, particularly if it is obvious or there is no choice in the matter.
    • 2013 June 22, “Snakes and ladders”, The Economist, volume 407, number 8841, page 76: 
      Risk is everywhere. From tabloid headlines insisting that coffee causes cancer (yesterday, of course, it cured it) to stern government warnings about alcohol and driving, the world is teeming with goblins. For each one there is a frighteningly precise measurement of just how likely it is to jump from the shadows and get you.
    Of course I know that!
    You will, of course, surrender all your future rights to the property.