hamartin
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English
[edit]Noun
[edit]hamartin (uncountable)
- (biochemistry) A peripheral membrane protein encoded in humans by the TSC1 gene, and implicated as a tumor suppressor.
- 2015 July 14, “Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness”, in PLOS ONE[1], :
- Notably, in breast cancer, relative low expression of hamartin and tuberin (TSC1 and TSC2 products, respectively) is associated with poor clinical outcome, and depletion of tuberin promotes metastasis.