1540s, from Latin sūppuratiō.
suppuration (countable and uncountable, plural suppurations)
- (medicine) Decay in tissue producing pus, or the pus itself.
- (medicine) The act of suppurating.
1600-1700, Arbuthnot, John, An essay concerning the effects of air on human bodies, page 178:
by the Inflammation and Suppuration of the axillary, inguinal, and other Glands, or in beginning Gangrenes...
decay in tissue producing pus