- The county town of Staffordshire, England.
- An unincorporated community in Humboldt County, California, USA.
- A town in Tolland County, Connecticut, USA.
- A small city in Stafford County, Kansas, USA.
- An unincorporated community in Holt County, Nebraska, USA.
- A town in Genesee County, New York, USA.
- A village in Monroe County, Ohio, USA.
- A city in Fort Bend and Harris Counties, Texas, USA.
- A CDP in and the county seat of Stafford County, Virginia, USA; also known as Stafford Courthouse.
- A suburb of Brisbane, Queensland, Australia.
- An industrial suburb in Johannesburg, South Africa.
- An English habitational surname from the place name.